Publications

2017

Liang et al. Phase-plate cryo-EM structure of a class B GPCR–G-protein complex. Nature 2017, doi:10.1038/nature22327
https://www.nature.com/articles/nature22327

Zhang et al. Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein. Nature 2017, doi:10.1038/nature22394
https://www.nature.com/articles/nature22394

2016

Manglik et al. Nanobodies to study G protein-coupled receptor structure and function. Annu. Rev. Pharmacol. Toxicol. 2017, doi:10.1146/annurevpharmtox-010716-104710
https://www.annualreviews.org/doi/abs/10.1146/annurev-pharmtox-010716-104710

2015

Marta Filizola (ed.), G Protein-Coupled Receptors in Drug Discovery: Methods and Protocols, Methods in Molecular Biology, vol. 1335, doi:10.1007/978-1-4939-2914-6_3
https://www.springer.com/gp/book/9781493929139

2014

Pardon et al. A general protocol for the generation of nanobodies for structural biology. Nature Protocol 2014, doi:10.1038/nprot.2014.039
https://www.nature.com/articles/nprot.2014.039

2011

Rasmussen et al. Crystal structure of the β2 adrenergic receptor–Gs protein complex. Nature 2011, doi:10.1038/nature10361
https://www.nature.com/articles/nature10361

Westfield et al. Structural flexibility of the Gαs α-helical domain in the β2-adrenoceptor Gs complex. PNAS 2011, doi:10.1073/pnas.1113645108
https://www.pnas.org/content/108/38/16086

Rasmussen et al. Structure of a nanobody-stabilized active state of the β2 adrenoceptor. Nature 2011, doi:10.1038/nature09648
https://www.nature.com/articles/nature09648

2018

Pardon et al. Nanobody-enabled reverse pharmacology on GPCRs. Angew. Chem. Int. Ed. doi:10.1002/anie.201712581
https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201712581

2019

Laverty et al. Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer. Nature 2019, doi:10.138/s41586-018-0833-4
https://www.nature.com/articles/s41586-018-0833-4

Masiulis et al. GABAA receptor signaling mechanisms revealed by structural pharmacology. Nature 2019, doi:10.1038/s41586-018-0832-5
https://www.nature.com/articles/s41586-018-0832-5?WT.feed_name=subjects_drug-discovery

2018

Stoeber et al. A genetically encoded biosensor reveals location bias of opioid drug action. Neuron 2018, doi: https://doi.org/10.1016/j.neuron.2018.04.021
https://www.cell.com/neuron/fulltext/S0896-6273(18)30329-5

2017

Sungkaworn et al. Single-molecule imaging reveals receptor–G protein interactions at cell surface hot spots. Nature 2017, doi:10.1038/nature24264
https://www.nature.com/articles/nature24264?WT.feed_name=subjects_molecular-biology

2013

Irannejad et al. Conformational biosensors reveal GPCR signaling from endosomes. Nature 2013, doi:10.1038/nature12000
https://www.nature.com/articles/nature12000

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